“A new device tested in pigs enables monitoring and early detection of pH changes in deep tissues due to post-operative leaks following gastrointestinal surgery. Such leaks – which occur at high rates 3-7 days following surgery – can be fatal if overlooked, and as such, require constant monitoring. Yet, early detection of these leaks remains a challenge.
To address this need, Jaiqi Liu and colleagues developed a novel class of pH-responsive materials for real-time ultrasound measurement of pH changes indicative of leaks from healing surgical joins following gastrointestinal surgery. They dubbed their bioresorbable, shape-adaptive, ultrasound-readable materials structure, ‘BioSUM.’ The thin and implantable device is comprised of small metal discs within a pH-responsive hydrogel. During recovery, the distance between the metal discs can be measured using ultrasound. Should a leak occur, the hydrogel reacts to the change in pH and swells, pushing the metal discs further apart, signaling a complication.”
Learn more: Liu, J., et al. (2024) Bioresorbable shape-adaptive structures for ultrasonic monitoring of deep-tissue homeostasis. Science. doi.org/10.1126/science.adk9880.
Family Medicine Residency Site: Abbotsford-Mission 